Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer
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چکیده
منابع مشابه
Post-Transcriptional Gene Regulation by MicroRNA and RNA-Binding Protein
Recent advanced studies have demonstrated that post-transcriptional gene regulation is involved in many aspects of biological processes and in the pathogenesis of various types of disorders, such as neurodegenerative diseases, autoimmune diseases, and cancer. In addition to transcriptional regulation, spatially and temporally regulated gene expression is achieved by the post-transcriptional con...
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Androgen ablation therapy is widely used for the treatment of advanced prostate cancer. However, the effectiveness of this intervention strategy is generally short-lived as the disease ultimately progresses to a hormone-refractory state. In recent years, it has become clear that even in antiandrogen-resistant cancers the androgen receptor (AR) signaling axis is intact and is required for prosta...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2021
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2020.108585